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FGFR-gerichtete Therapie von Kopf-Hals-Karzinomen

BACKGROUND: Genomic aberrations (mutations, gene fusions, amplifications) and dysregulation of the fibroblast growth factor (FGF) receptor (FGFR) signaling pathway are frequently found in squamous cell carcinomas of the head and neck (HNSCCs). Targeted therapy with tyrosine kinase inhibitors (TKIs)...

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Detalles Bibliográficos
Autor principal: Dietrich, Dimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Medizin 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902560/
https://www.ncbi.nlm.nih.gov/pubmed/32519203
http://dx.doi.org/10.1007/s00106-020-00893-2

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