The extracellular lactate-to-pyruvate ratio modulates the sensitivity to oxidative stress-induced apoptosis via the cytosolic NADH/NAD(+) redox state

The advantages of the Warburg effect on tumor growth and progression are well recognized. However, the relevance of the Warburg effect for the inherent resistance to apoptosis of cancer cells has received much less attention. Here, we show here that the Warburg effect modulates the extracellular lac...

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Detalles Bibliográficos
Autores principales: Go, Simei, Kramer, Thorquil T., Verhoeven, Arthur J., Oude Elferink, Ronald P. J., Chang, Jung-Chin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902596/
https://www.ncbi.nlm.nih.gov/pubmed/33230593
http://dx.doi.org/10.1007/s10495-020-01648-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902596/
https://www.ncbi.nlm.nih.gov/pubmed/33230593
http://dx.doi.org/10.1007/s10495-020-01648-8

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