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Metabolic labeling with an alkyne probe reveals similarities and differences in the prenylomes of several brain-derived cell lines and primary cells

Protein prenylation involves the attachment of one or two isoprenoid group(s) onto cysteine residues positioned near the C-terminus. This modification is essential for many signal transduction processes. In this work, the use of the probe C15AlkOPP for metabolic labeling and identification of prenyl...

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Detalles Bibliográficos
Autores principales: Suazo, Kiall F., Jeong, Angela, Ahmadi, Mina, Brown, Caroline, Qu, Wenhui, Li, Ling, Distefano, Mark D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902609/
https://www.ncbi.nlm.nih.gov/pubmed/33623102
http://dx.doi.org/10.1038/s41598-021-83666-3