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Metabolic labeling with an alkyne probe reveals similarities and differences in the prenylomes of several brain-derived cell lines and primary cells
Protein prenylation involves the attachment of one or two isoprenoid group(s) onto cysteine residues positioned near the C-terminus. This modification is essential for many signal transduction processes. In this work, the use of the probe C15AlkOPP for metabolic labeling and identification of prenyl...
Autores principales: | Suazo, Kiall F., Jeong, Angela, Ahmadi, Mina, Brown, Caroline, Qu, Wenhui, Li, Ling, Distefano, Mark D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902609/ https://www.ncbi.nlm.nih.gov/pubmed/33623102 http://dx.doi.org/10.1038/s41598-021-83666-3 |
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