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Triptonide is a reversible non-hormonal male contraceptive agent in mice and non-human primates

There are no non-hormonal male contraceptives currently on the market despite decades of efforts toward the development of “male pills”. Here, we report that triptonide, a natural compound purified from the Chinese herb Tripterygium Wilfordii Hook F displays reversible male contraceptive effects in...

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Detalles Bibliográficos
Autores principales: Chang, Zongliang, Qin, Weibing, Zheng, Huili, Schegg, Kathleen, Han, Lu, Liu, Xiaohua, Wang, Yue, Wang, Zhuqing, McSwiggin, Hayden, Peng, Hongying, Yuan, Shuiqiao, Wu, Jiabao, Wang, Yongxia, Zhu, Shenghui, Jiang, Yanjia, Nie, Hua, Tang, Yuan, Zhou, Yu, Hitchcock, Michael J. M., Tang, Yunge, Yan, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902613/
https://www.ncbi.nlm.nih.gov/pubmed/33623031
http://dx.doi.org/10.1038/s41467-021-21517-5