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Systematic functional analysis of Leishmania protein kinases identifies regulators of differentiation or survival

Differentiation between distinct stages is fundamental for the life cycle of intracellular protozoan parasites and for transmission between hosts, requiring stringent spatial and temporal regulation. Here, we apply kinome-wide gene deletion and gene tagging in Leishmania mexicana promastigotes to de...

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Detalles Bibliográficos
Autores principales: Baker, N., Catta-Preta, C. M. C., Neish, R., Sadlova, J., Powell, B., Alves-Ferreira, E. V. C., Geoghegan, V., Carnielli, J. B. T., Newling, K., Hughes, C., Vojtkova, B., Anand, J., Mihut, A., Walrad, P. B., Wilson, L. G., Pitchford, J. W., Volf, P., Mottram, J. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902614/
https://www.ncbi.nlm.nih.gov/pubmed/33623024
http://dx.doi.org/10.1038/s41467-021-21360-8