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Systematic functional analysis of Leishmania protein kinases identifies regulators of differentiation or survival
Differentiation between distinct stages is fundamental for the life cycle of intracellular protozoan parasites and for transmission between hosts, requiring stringent spatial and temporal regulation. Here, we apply kinome-wide gene deletion and gene tagging in Leishmania mexicana promastigotes to de...
Autores principales: | Baker, N., Catta-Preta, C. M. C., Neish, R., Sadlova, J., Powell, B., Alves-Ferreira, E. V. C., Geoghegan, V., Carnielli, J. B. T., Newling, K., Hughes, C., Vojtkova, B., Anand, J., Mihut, A., Walrad, P. B., Wilson, L. G., Pitchford, J. W., Volf, P., Mottram, J. C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902614/ https://www.ncbi.nlm.nih.gov/pubmed/33623024 http://dx.doi.org/10.1038/s41467-021-21360-8 |
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