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An ESCRT-dependent step in fatty acid transfer from lipid droplets to mitochondria through VPS13D−TSG101 interactions

Upon starvation, cells rewire their metabolism, switching from glucose-based metabolism to mitochondrial oxidation of fatty acids, which require the transfer of FAs from lipid droplets (LDs) to mitochondria at mitochondria−LD membrane contact sites (MCSs). However, factors responsible for FA transfe...

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Detalles Bibliográficos
Autores principales: Wang, Jingru, Fang, Na, Xiong, Juan, Du, Yuanjiao, Cao, Yue, Ji, Wei-Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902631/
https://www.ncbi.nlm.nih.gov/pubmed/33623047
http://dx.doi.org/10.1038/s41467-021-21525-5