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Melanocortin receptor activation alleviates amyloid pathology and glial reactivity in an Alzheimer’s disease transgenic mouse model

Alzheimer’s disease (AD) is a devastating neurodegenerative disorder with no disease-modifying treatment. AD progression is characterized by cognitive decline, neuroinflammation, and accumulation of amyloid-beta (Aβ) and neurofibrillary tangles in the brain, leading to neuronal and glial dysfunction...

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Detalles Bibliográficos
Autores principales: Lau, Jackie K. Y., Tian, Min, Shen, Yang, Lau, Shun-Fat, Fu, Wing-Yu, Fu, Amy K. Y., Ip, Nancy Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902646/
https://www.ncbi.nlm.nih.gov/pubmed/33623128
http://dx.doi.org/10.1038/s41598-021-83932-4