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3D Cell Culture for the Study of Microenvironment-Mediated Mechanostimuli to the Cell Nucleus: An Important Step for Cancer Research

The discovery that the stiffness of the tumor microenvironment (TME) changes during cancer progression motivated the development of cell culture involving extracellular mechanostimuli, with the intent of identifying mechanotransduction mechanisms that influence cell phenotypes. Collagen I is a main...

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Detalles Bibliográficos
Autores principales: Chhetri, Apekshya, Rispoli, Joseph V., Lelièvre, Sophie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902798/
https://www.ncbi.nlm.nih.gov/pubmed/33644116
http://dx.doi.org/10.3389/fmolb.2021.628386