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Using protein turnover to expand the applications of transcriptomics

RNA expression and protein abundance are often at odds when measured in parallel, raising questions about the functional implications of transcriptomics data. Here, we present the concept of persistence, which attempts to address this challenge by combining protein half-life data with RNA expression...

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Detalles Bibliográficos
Autores principales: Smail, Marissa A., Reigle, James K., McCullumsmith, Robert E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902815/
https://www.ncbi.nlm.nih.gov/pubmed/33623108
http://dx.doi.org/10.1038/s41598-021-83886-7