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Generation of reconstituted hemato-lymphoid murine embryos by placental transplantation into embryos lacking HSCs
In order to increase the contribution of donor HSC cells, irradiation and DNA alkylating agents have been commonly used as experimental methods to eliminate HSCs for adult mice. But a technique of HSC deletion for mouse embryo for increase contribution of donor cells has not been published. Here, we...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902833/ https://www.ncbi.nlm.nih.gov/pubmed/33623082 http://dx.doi.org/10.1038/s41598-021-83652-9 |