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Generation of reconstituted hemato-lymphoid murine embryos by placental transplantation into embryos lacking HSCs

In order to increase the contribution of donor HSC cells, irradiation and DNA alkylating agents have been commonly used as experimental methods to eliminate HSCs for adult mice. But a technique of HSC deletion for mouse embryo for increase contribution of donor cells has not been published. Here, we...

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Detalles Bibliográficos
Autores principales: Jeon, Hyojung, Asano, Keigo, Wakimoto, Arata, Kulathunga, Kaushalya, Tran, Mai Thi Nhu, Nakamura, Megumi, Yokomizo, Tomomasa, Hamada, Michito, Takahashi, Satoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902833/
https://www.ncbi.nlm.nih.gov/pubmed/33623082
http://dx.doi.org/10.1038/s41598-021-83652-9