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A rotary mechanism for allostery in bacterial hybrid malic enzymes
Bacterial hybrid malic enzymes (MaeB grouping, multidomain) catalyse the transformation of malate to pyruvate, and are a major contributor to cellular reducing power and carbon flux. Distinct from other malic enzyme subtypes, the hybrid enzymes are regulated by acetyl-CoA, a molecular indicator of t...
Autores principales: | Harding, Christopher John, Cadby, Ian Thomas, Moynihan, Patrick Joseph, Lovering, Andrew Lee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902834/ https://www.ncbi.nlm.nih.gov/pubmed/33623032 http://dx.doi.org/10.1038/s41467-021-21528-2 |
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