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Dl-3-n-Butylphthalide Reduces Cognitive Deficits and Alleviates Neuropathology in P301S Tau Transgenic Mice

Alzheimer’s disease (AD) is a destructive and burdensome neurodegenerative disease, one of the most common characteristics of which are neurofibrillary tangles (NFTs) that are composed of abnormal tau protein. Animal studies have suggested that dl-3-n-butylphthalide (dl-NBP) alleviates cognitive imp...

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Detalles Bibliográficos
Autores principales: Chang, Yanmin, Yao, Yi, Ma, Rong, Wang, Zemin, Hu, Junjie, Wu, Yanqing, Jiang, Xingjun, Li, Lulu, Li, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902884/
https://www.ncbi.nlm.nih.gov/pubmed/33642981
http://dx.doi.org/10.3389/fnins.2021.620176