Systemic Candesartan Treatment Modulates Behavior, Synaptic Protein Levels, and Neuroinflammation in Female Mice That Express Human APOE4

Evidence suggests that angiotensin receptor blockers (ARBs) could be beneficial for Alzheimer’s disease (AD) patients independent of any effects on hypertension. However, studies in rodent models directly testing the activity of ARB treatment on behavior and AD-relevent pathology including neuroinfl...

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Detalles Bibliográficos
Autores principales: Scheinman, Sarah B., Zaldua, Steve, Dada, Adedoyin, Krochmaliuk, Kateryna, Dye, Katherine, Marottoli, Felecia M., Thatcher, Gregory R. J., Tai, Leon M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902885/
https://www.ncbi.nlm.nih.gov/pubmed/33642985
http://dx.doi.org/10.3389/fnins.2021.628403

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902885/
https://www.ncbi.nlm.nih.gov/pubmed/33642985
http://dx.doi.org/10.3389/fnins.2021.628403

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