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Negative Impact of Sigma-1 Receptor Agonist Treatment on Tissue Integrity and Motor Function Following Spinal Cord Injury

In traumatic spinal cord injury, the initial trauma is followed by a cascade of impairments, including excitotoxicity and calcium overload, which ultimately induces secondary damages. The sigma-1 receptor is widely expressed in the central nervous system and is acknowledged to play a key role in cal...

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Detalles Bibliográficos
Autores principales: Lattard, Alise, Poulen, Gaëtan, Bartolami, Sylvain, Gerber, Yannick N., Perrin, Florence E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902910/
https://www.ncbi.nlm.nih.gov/pubmed/33643047
http://dx.doi.org/10.3389/fphar.2021.614949