TFEB deficiency attenuates mitochondrial degradation upon brown adipose tissue whitening at thermoneutrality

OBJECTIVE: Brown adipose tissue (BAT) thermogenesis offers the potential to improve metabolic health in mice and humans. However, humans predominantly live under thermoneutral conditions, leading to BAT whitening, a reduction in BAT mitochondrial content and metabolic activity. Recent studies have e...

Descripción completa

Detalles Bibliográficos
Autores principales: Sass, Frederike, Schlein, Christian, Jaeckstein, Michelle Y., Pertzborn, Paul, Schweizer, Michaela, Schinke, Thorsten, Ballabio, Andrea, Scheja, Ludger, Heeren, Joerg, Fischer, Alexander W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7903014/
https://www.ncbi.nlm.nih.gov/pubmed/33516944
http://dx.doi.org/10.1016/j.molmet.2021.101173

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7903014/
https://www.ncbi.nlm.nih.gov/pubmed/33516944
http://dx.doi.org/10.1016/j.molmet.2021.101173

Ejemplares similares