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Borrelidin from Saltern-Derived Halophilic Nocardiopsis sp. Dissociates Amyloid-β and Tau Fibrils

BACKGROUND: Alzheimer’s disease (AD) is characterized by the aggregation of two pathological proteins, amyloid-β (Aβ) and tau, leading to neuronal and cognitive dysfunction. Clearance of either Aβ or tau aggregates by immunotherapy has become a potential therapy, as these aggregates are found in the...

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Detalles Bibliográficos
Autores principales: Shin, Jisu, Yang, Seung-Hoon, Du, Young Eun, Park, Keunwan, Kim, DaWon, Shin, Daniel, Kim, Jungwoo, Kim, Seong-Hwan, Kim, Yun Kyung, Shin, Jongheon, Oh, Dong-Chan, Kim, YoungSoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7903018/
https://www.ncbi.nlm.nih.gov/pubmed/33681712
http://dx.doi.org/10.3233/ADR-200247