Acute Intestinal Inflammation Depletes/Recruits Histamine-Expressing Myeloid Cells From the Bone Marrow Leading to Exhaustion of MB-HSCs

BACKGROUND & AIMS: Histidine decarboxylase (HDC), the histamine-synthesizing enzyme, is expressed in a subset of myeloid cells but also marks quiescent myeloid-biased hematopoietic stem cells (MB-HSCs) that are activated upon myeloid demand injury. However, the role of MB-HSCs in dextran sulfate...

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Detalles Bibliográficos
Autores principales: Fu, Na, Wu, Feijing, Jiang, Zhengyu, Kim, Woosook, Ruan, Tuo, Malagola, Ermanno, Ochiai, Yosuke, Nápoles, Osmel Companioni, Valenti, Giovanni, White, Ruth A., Belin, Bryana R., Zamechek, Leah B., LaBella, Jonathan S., Wang, Timothy C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7903065/
https://www.ncbi.nlm.nih.gov/pubmed/33249238
http://dx.doi.org/10.1016/j.jcmgh.2020.11.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7903065/
https://www.ncbi.nlm.nih.gov/pubmed/33249238
http://dx.doi.org/10.1016/j.jcmgh.2020.11.007

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