Discovery of novel inhibitors against main protease (Mpro) of SARS-CoV-2 via virtual screening and biochemical evaluation

SARS-CoV-2 is the pathogen that caused the global COVID-19 outbreak in 2020. Promising progress has been made in developing vaccines and antiviral drugs. Antivirals medicines are necessary complements of vaccines for post-infection treatment. The main protease (Mpro) is an extremely important protea...

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Detalles Bibliográficos
Autores principales: Guo, Sheng, Xie, Hang, Lei, Yu, Liu, Bin, Zhang, Li, Xu, Yechun, Zuo, Zhili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7903152/
https://www.ncbi.nlm.nih.gov/pubmed/33667900
http://dx.doi.org/10.1016/j.bioorg.2021.104767

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7903152/
https://www.ncbi.nlm.nih.gov/pubmed/33667900
http://dx.doi.org/10.1016/j.bioorg.2021.104767

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