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Discovery of novel inhibitors against main protease (Mpro) of SARS-CoV-2 via virtual screening and biochemical evaluation

SARS-CoV-2 is the pathogen that caused the global COVID-19 outbreak in 2020. Promising progress has been made in developing vaccines and antiviral drugs. Antivirals medicines are necessary complements of vaccines for post-infection treatment. The main protease (Mpro) is an extremely important protea...

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Detalles Bibliográficos
Autores principales:	Guo, Sheng, Xie, Hang, Lei, Yu, Liu, Bin, Zhang, Li, Xu, Yechun, Zuo, Zhili
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Inc. 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7903152/ https://www.ncbi.nlm.nih.gov/pubmed/33667900 http://dx.doi.org/10.1016/j.bioorg.2021.104767

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