Cargando…

Single-nucleotide methylation specifically represses type I interferon in antiviral innate immunity

Frequent outbreaks of viruses have caused a serious threat to public health. Previous evidence has revealed that DNA methylation is correlated with viral infections, but its role in innate immunity remains poorly investigated. Additionally, DNA methylation inhibitors promote IFN-I by upregulating en...

Descripción completa

Detalles Bibliográficos
Autores principales: Gao, Zheng-jun, Li, Wen-ping, Mao, Xin-tao, Huang, Tao, Wang, Hao-li, Li, Yi-ning, Liu, Bao-qin, Zhong, Jiang-yan, Renjie, Chai, Jin, Jin, Li, Yi-yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7903198/
https://www.ncbi.nlm.nih.gov/pubmed/33616624
http://dx.doi.org/10.1084/jem.20201798