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Mismatch Repair Universal Screening of Endometrial Cancers (MUSE) in a Canadian Cohort

Background: Approximately 2–6% of endometrial cancers (ECs) are due to Lynch Syndrome (LS), a cancer predisposition syndrome caused by germline pathogenic variants (PVs) affecting the DNA mismatch repair (MMR) pathway. Increasingly, universal tissue-based screening of ECs has been proposed as an eff...

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Detalles Bibliográficos
Autores principales: Lawrence, Jessica, Richer, Lara, Arseneau, Jocelyne, Zeng, Xing, Chong, George, Weber, Evan, Foulkes, William, Palma, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7903281/
https://www.ncbi.nlm.nih.gov/pubmed/33467402
http://dx.doi.org/10.3390/curroncol28010052