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Bazedoxifene Regulates Th17 Immune Response to Ameliorate Experimental Autoimmune myocarditis via Inhibition of STAT3 Activation

Myocarditis is a type of inflammatory cardiomyopathy that has no specific treatment. Accumulating evidence suggests that Th17 cells play a prominent role in the pathogenesis of myocarditis. Interleukin-(IL)-6-mediated signal transducer and activation of transcription 3 (STAT3) signaling is essential...

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Detalles Bibliográficos
Autores principales: Wang, Jing, Liu, Tianshu, Chen, Xiongwen, Jin, Qiaofeng, Chen, Yihan, Zhang, Li, Han, Zhengyang, Chen, Dandan, Li, Yuman, Lv, Qing, Xie, Mingxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7903338/
https://www.ncbi.nlm.nih.gov/pubmed/33643041
http://dx.doi.org/10.3389/fphar.2020.613160