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Cis-regulatory mutations with driver hallmarks in major cancers

Despite the recent availability of complete genome sequences of tumors from thousands of patients, isolating disease-causing (driver) non-coding mutations from the plethora of somatic variants remains challenging, and only a handful of validated examples exist. By integrating whole-genome sequencing...

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Detalles Bibliográficos
Autores principales: Cheng, Zhongshan, Vermeulen, Michael, Rollins-Green, Micheal, DeVeale, Brian, Babak, Tomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7903341/
https://www.ncbi.nlm.nih.gov/pubmed/33665563
http://dx.doi.org/10.1016/j.isci.2021.102144