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Effects of shRNA-mediated silencing of PDE5A3 on intracellular cGMP and free Ca(2+) levels and human prostate smooth muscle cell proliferation from benign prostatic hyperplasia

Benign prostatic hyperplasia (BPH) with lower urinary tract symptoms (LUTS) is a common disease among elderly men, for which safe and effective treatment strategies remain limited. The aim of the present study was to explore the potential effects of phosphodiesterase 5A3 (PDE5A3) silencing on human...

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Detalles Bibliográficos
Autores principales: Xu, Zheng, Ge, Yuzheng, Jiang, Ke, Xu, Luwei, Zhu, Jiageng, Zhou, Changcheng, Zhou, Liuhua, Jia, Ruipeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7903389/
https://www.ncbi.nlm.nih.gov/pubmed/33732295
http://dx.doi.org/10.3892/etm.2021.9753