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Effects of shRNA-mediated silencing of PDE5A3 on intracellular cGMP and free Ca(2+) levels and human prostate smooth muscle cell proliferation from benign prostatic hyperplasia
Benign prostatic hyperplasia (BPH) with lower urinary tract symptoms (LUTS) is a common disease among elderly men, for which safe and effective treatment strategies remain limited. The aim of the present study was to explore the potential effects of phosphodiesterase 5A3 (PDE5A3) silencing on human...
Autores principales: | Xu, Zheng, Ge, Yuzheng, Jiang, Ke, Xu, Luwei, Zhu, Jiageng, Zhou, Changcheng, Zhou, Liuhua, Jia, Ruipeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7903389/ https://www.ncbi.nlm.nih.gov/pubmed/33732295 http://dx.doi.org/10.3892/etm.2021.9753 |
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