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Generation of glioblastoma patient-derived organoids and mouse brain orthotopic xenografts for drug screening
Robust patient-derived platforms that recapitulate the cellular and molecular fingerprints of glioblastoma are crucial for developing effective therapies. Here, we describe a chemically defined protocol for 3D culture and propagation of glioblastoma in 3D gliospheres, patient-derived organoids (PDOs...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7903462/ https://www.ncbi.nlm.nih.gov/pubmed/33665625 http://dx.doi.org/10.1016/j.xpro.2021.100345 |