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The role of validation in establishing the scientific credibility of predictive toxicology approaches intended for regulatory application

New approaches in toxicology based on in vitro methods and computational modelling offer considerable potential to improve the efficiency and effectiveness of chemical hazard and risk assessment in a variety of regulatory contexts. However, this presents challenges both for developers and regulatory...

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Detalles Bibliográficos
Autores principales: Patterson, Eann A., Whelan, Maurice P., Worth, Andrew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7903516/
https://www.ncbi.nlm.nih.gov/pubmed/33681540
http://dx.doi.org/10.1016/j.comtox.2020.100144