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Chronic inflammation of middle ear cholesteatoma promotes its recurrence via a paracrine mechanism

BACKGROUND: Cholesteatoma disease is an expanding lesion in the middle ear. Hearing loss and facial paralysis alongside with other intracranial complications are found. No pharmaceutical treatment is available today and recurrence after surgical extraction occurs. We investigated possible TLR4-based...

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Detalles Bibliográficos
Autores principales: Schürmann, Matthias, Oppel, Felix, Shao, Senyao, Volland-Thurn, Verena, Kaltschmidt, Christian, Kaltschmidt, Barbara, Scholtz, Lars-Uwe, Sudhoff, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7903614/
https://www.ncbi.nlm.nih.gov/pubmed/33627146
http://dx.doi.org/10.1186/s12964-020-00690-y