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SEPHS1 promotes SMAD2/3/4 expression and hepatocellular carcinoma cells invasion

BACKGROUND: Hepatocellular carcinoma (HCC) is one of the common cancers that are very aggressive. The secreted cytokine transforming growth factor-β (TGF-β) promotes cancer metastasis by multiple mechanisms such as epithelial-mesenchymal transition and immune evasion. The canonical TGF-β signaling i...

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Detalles Bibliográficos
Autores principales: Yang, Shu, Zhang, Hongying, Yang, Hua, Zhang, Jin, Wang, Jiao, Luo, Ting, Jiang, Yangfu, Hua, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7903722/
https://www.ncbi.nlm.nih.gov/pubmed/33622411
http://dx.doi.org/10.1186/s40164-021-00212-7