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Long-term live imaging and multiscale analysis identify heterogeneity and core principles of epithelial organoid morphogenesis
BACKGROUND: Organoids are morphologically heterogeneous three-dimensional cell culture systems and serve as an ideal model for understanding the principles of collective cell behaviour in mammalian organs during development, homeostasis, regeneration, and pathogenesis. To investigate the underlying...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7903752/ https://www.ncbi.nlm.nih.gov/pubmed/33627108 http://dx.doi.org/10.1186/s12915-021-00958-w |