Long-term live imaging and multiscale analysis identify heterogeneity and core principles of epithelial organoid morphogenesis

BACKGROUND: Organoids are morphologically heterogeneous three-dimensional cell culture systems and serve as an ideal model for understanding the principles of collective cell behaviour in mammalian organs during development, homeostasis, regeneration, and pathogenesis. To investigate the underlying...

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Detalles Bibliográficos
Autores principales: Hof, Lotta, Moreth, Till, Koch, Michael, Liebisch, Tim, Kurtz, Marina, Tarnick, Julia, Lissek, Susanna M., Verstegen, Monique M. A., van der Laan, Luc J. W., Huch, Meritxell, Matthäus, Franziska, Stelzer, Ernst H. K., Pampaloni, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7903752/
https://www.ncbi.nlm.nih.gov/pubmed/33627108
http://dx.doi.org/10.1186/s12915-021-00958-w

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