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Increased ribosomal protein levels and protein synthesis in the striatal synaptosome of Shank3-overexpressing transgenic mice

The SH3 and multiple ankyrin repeat domains 3 (Shank3) protein is a core organizer of the macromolecular complex in excitatory postsynapses, and its defects cause numerous synaptopathies, including autism spectrum disorders. Although the function of Shank3 as a postsynaptic scaffold is adequately es...

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Detalles Bibliográficos
Autores principales: Jin, Chunmei, Lee, Yeunkum, Kang, Hyojin, Jeong, Kwon, Park, Joori, Zhang, Yinhua, Kang, Hyae Rim, Ma, Ruiying, Seong, Hyunyoung, Kim, Yoonhee, Jung, Hosung, Kim, Jin Young, Kim, Yoon Ki, Han, Kihoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7903774/
https://www.ncbi.nlm.nih.gov/pubmed/33622379
http://dx.doi.org/10.1186/s13041-021-00756-z