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TRIM47 promotes malignant progression of renal cell carcinoma by degrading P53 through ubiquitination
BACKGROUND: Renal cell carcinoma (RCC) is one of the most common malignant tumors originating from the renal parenchymal urinary epithelial system. Tripartite motif 47 (TRIM47) is a member of the TRIM family proteins, which has E3 ligase activity and has been demonstrated to be involved in the occur...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7903798/ https://www.ncbi.nlm.nih.gov/pubmed/33622324 http://dx.doi.org/10.1186/s12935-021-01831-0 |