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TRIM47 promotes malignant progression of renal cell carcinoma by degrading P53 through ubiquitination

BACKGROUND: Renal cell carcinoma (RCC) is one of the most common malignant tumors originating from the renal parenchymal urinary epithelial system. Tripartite motif 47 (TRIM47) is a member of the TRIM family proteins, which has E3 ligase activity and has been demonstrated to be involved in the occur...

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Detalles Bibliográficos
Autores principales: Chen, Jia-xin, Xu, Da, Cao, Jian-wei, Zuo, Li, Han, Zhi-tao, Tian, Yi-jun, Chu, Chuan-min, Zhou, Wang, Pan, Xiu-wu, Cui, Xin-gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7903798/
https://www.ncbi.nlm.nih.gov/pubmed/33622324
http://dx.doi.org/10.1186/s12935-021-01831-0