Genetic background modifies vulnerability to glaucoma-related phenotypes in Lmx1b mutant mice

Variants in the LIM homeobox transcription factor 1-beta (LMX1B) gene predispose individuals to elevated intraocular pressure (IOP), a key risk factor for glaucoma. However, the effect of LMX1B mutations varies widely between individuals. To better understand the mechanisms underlying LMX1B-related...

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Detalles Bibliográficos
Autores principales: Tolman, Nicholas G., Balasubramanian, Revathi, Macalinao, Danilo G., Kearney, Alison L., MacNicoll, Katharine H., Montgomery, Christa L., de Vries, Wilhelmine N., Jackson, Ian J., Cross, Sally H., Kizhatil, Krishnakumar, Nair, K. Saidas, John, Simon W. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7903917/
https://www.ncbi.nlm.nih.gov/pubmed/33462143
http://dx.doi.org/10.1242/dmm.046953

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7903917/
https://www.ncbi.nlm.nih.gov/pubmed/33462143
http://dx.doi.org/10.1242/dmm.046953

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