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Silencing of PTPN18 Induced Ferroptosis in Endometrial Cancer Cells Through p-P38-Mediated GPX4/xCT Down-Regulation

BACKGROUND: Endometrial cancer (EC) is the fourth most common neoplasm and the eighth leading cause of cancer death in females worldwide. PTPN18 is a member of the protein tyrosine phosphatases (PTP) family, which is associated with the occurrence and progression of various human cancers. PTPN18 was...

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Detalles Bibliográficos
Autores principales: Wang, Haibo, Peng, Siyuan, Cai, Junhong, Bao, Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7903946/
https://www.ncbi.nlm.nih.gov/pubmed/33642877
http://dx.doi.org/10.2147/CMAR.S278728