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Splicing machinery dysregulation drives glioblastoma development/aggressiveness: oncogenic role of SRSF3

Glioblastomas remain the deadliest brain tumour, with a dismal ∼12–16-month survival from diagnosis. Therefore, identification of new diagnostic, prognostic and therapeutic tools to tackle glioblastomas is urgently needed. Emerging evidence indicates that the cellular machinery controlling the splic...

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Detalles Bibliográficos
Autores principales: Fuentes-Fayos, Antonio C, Vázquez-Borrego, Mari C, Jiménez-Vacas, Juan M, Bejarano, Leire, Pedraza-Arévalo, Sergio, L.-López, Fernando, Blanco-Acevedo, Cristóbal, Sánchez-Sánchez, Rafael, Reyes, Oscar, Ventura, Sebastián, Solivera, Juan, Breunig, Joshua J, Blasco, María A, Gahete, Manuel D, Castaño, Justo P, Luque, Raúl M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904102/
https://www.ncbi.nlm.nih.gov/pubmed/33141183
http://dx.doi.org/10.1093/brain/awaa273