A robust method for the detection of small changes in relaxation parameters and free water content in the vicinity of the substantia nigra in Parkinson’s disease patients

Alterations in the substantia nigra are strongly associated with Parkinson’s disease. However, due to low contrast and partial volume effects present in typical MRI images, the substantia nigra is not of sufficient size to obtain a reliable segmentation for region-of-interest based analysis. To comb...

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Detalles Bibliográficos
Autores principales: Dzieciol, Krzysztof, Iordanishvili, Elene, Abbas, Zaheer, Nahimi, Adjmal, Winterdahl, Michael, Shah, N. Jon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904163/
https://www.ncbi.nlm.nih.gov/pubmed/33626092
http://dx.doi.org/10.1371/journal.pone.0247552

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904163/
https://www.ncbi.nlm.nih.gov/pubmed/33626092
http://dx.doi.org/10.1371/journal.pone.0247552

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