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A robust method for the detection of small changes in relaxation parameters and free water content in the vicinity of the substantia nigra in Parkinson’s disease patients
Alterations in the substantia nigra are strongly associated with Parkinson’s disease. However, due to low contrast and partial volume effects present in typical MRI images, the substantia nigra is not of sufficient size to obtain a reliable segmentation for region-of-interest based analysis. To comb...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904163/ https://www.ncbi.nlm.nih.gov/pubmed/33626092 http://dx.doi.org/10.1371/journal.pone.0247552 |