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Calcium ions trigger the exposure of phosphatidylserine on the surface of necrotic cells
Intracellular Ca(2+) level is under strict regulation through calcium channels and storage pools including the endoplasmic reticulum (ER). Mutations in certain ion channel subunits, which cause mis-regulated Ca(2+) influx, induce the excitotoxic necrosis of neurons. In the nematode Caenorhabditis el...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904182/ https://www.ncbi.nlm.nih.gov/pubmed/33571185 http://dx.doi.org/10.1371/journal.pgen.1009066 |