New sulphonamide pyrolidine carboxamide derivatives: Synthesis, molecular docking, antiplasmodial and antioxidant activities

Carboxamides bearing sulphonamide functionality have been shown to exhibit significant lethal effect on Plasmodium falciparum, the causative agent of human malaria. Here we report the synthesis of thirty-two new drug-like sulphonamide pyrolidine carboxamide derivatives and their antiplasmodial and a...

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Detalles Bibliográficos
Autores principales: Onoabedje, Efeturi A., Ibezim, Akachukwu, Okoro, Uchechukwu C., Batra, Sanjay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904193/
https://www.ncbi.nlm.nih.gov/pubmed/33626047
http://dx.doi.org/10.1371/journal.pone.0243305

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904193/
https://www.ncbi.nlm.nih.gov/pubmed/33626047
http://dx.doi.org/10.1371/journal.pone.0243305

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