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Cardiometabolic risks and atherosclerotic disease in ApoE knockout mice: Effect of spinal cord injury and Salsalate anti-inflammatory pharmacotherapy

OBJECTIVE: To test in mice with a double mutation of the ApoE gene (ApoE(-/-)) whether spinal cord injury (SCI) hastens the native trajectory of, and established component risks for, atherosclerotic disease (AD), and whether Salsalate anti-inflammatory pharmacotherapy attenuates the impact of SCI. M...

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Detalles Bibliográficos
Autores principales: Bigford, Gregory E., Szeto, Angela, Kimball, John, Herderick, Edward E., Mendez, Armando J., Nash, Mark S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904230/
https://www.ncbi.nlm.nih.gov/pubmed/33626069
http://dx.doi.org/10.1371/journal.pone.0246601