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State-dependent protein-lipid interactions of a pentameric ligand-gated ion channel in a neuronal membrane

Pentameric ligand-gated ion channels (pLGICs) are receptor proteins that are sensitive to their membrane environment, but the mechanism for how lipids modulate function under physiological conditions in a state dependent manner is not known. The glycine receptor is a pLGIC whose structure has been r...

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Detalles Bibliográficos
Autores principales: Dämgen, Marc A., Biggin, Philip C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904231/
https://www.ncbi.nlm.nih.gov/pubmed/33571182
http://dx.doi.org/10.1371/journal.pcbi.1007856