Total predicted MHC-I epitope load is inversely associated with population mortality from SARS-CoV-2

Polymorphisms in MHC-I protein sequences across human populations significantly affect viral peptide binding capacity, and thus alter T cell immunity to infection. In the present study, we assess the relationship between observed SARS-CoV-2 population mortality and the predicted viral binding capaci...

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Detalles Bibliográficos
Autores principales: Wilson, Eric A., Hirneise, Gabrielle, Singharoy, Abhishek, Anderson, Karen S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904449/
https://www.ncbi.nlm.nih.gov/pubmed/33649748
http://dx.doi.org/10.1016/j.xcrm.2021.100221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904449/
https://www.ncbi.nlm.nih.gov/pubmed/33649748
http://dx.doi.org/10.1016/j.xcrm.2021.100221

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