TLR4 and CD14 trafficking and its influence on LPS-induced pro-inflammatory signaling

Toll-like receptor (TLR) 4 belongs to the TLR family of receptors inducing pro-inflammatory responses to invading pathogens. TLR4 is activated by lipopolysaccharide (LPS, endotoxin) of Gram-negative bacteria and sequentially triggers two signaling cascades: the first one involving TIRAP and MyD88 ad...

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Detalles Bibliográficos
Autores principales: Ciesielska, Anna, Matyjek, Marta, Kwiatkowska, Katarzyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904555/
https://www.ncbi.nlm.nih.gov/pubmed/33057840
http://dx.doi.org/10.1007/s00018-020-03656-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904555/
https://www.ncbi.nlm.nih.gov/pubmed/33057840
http://dx.doi.org/10.1007/s00018-020-03656-y

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