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TLR4 and CD14 trafficking and its influence on LPS-induced pro-inflammatory signaling

Toll-like receptor (TLR) 4 belongs to the TLR family of receptors inducing pro-inflammatory responses to invading pathogens. TLR4 is activated by lipopolysaccharide (LPS, endotoxin) of Gram-negative bacteria and sequentially triggers two signaling cascades: the first one involving TIRAP and MyD88 ad...

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Detalles Bibliográficos
Autores principales:	Ciesielska, Anna, Matyjek, Marta, Kwiatkowska, Katarzyna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904555/ https://www.ncbi.nlm.nih.gov/pubmed/33057840 http://dx.doi.org/10.1007/s00018-020-03656-y

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