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Bassoon inhibits proteasome activity via interaction with PSMB4

ABSTRACT: Proteasomes are protein complexes that mediate controlled degradation of damaged or unneeded cellular proteins. In neurons, proteasome regulates synaptic function and its dysfunction has been linked to neurodegeneration and neuronal cell death. However, endogenous mechanisms controlling pr...

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Detalles Bibliográficos
Autores principales: Montenegro-Venegas, Carolina, Fienko, Sandra, Anni, Daniela, Pina-Fernández, Eneko, Frischknecht, Renato, Fejtova, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904567/
https://www.ncbi.nlm.nih.gov/pubmed/32651614
http://dx.doi.org/10.1007/s00018-020-03590-z