Cell type-selective secretome profiling in vivo

Secreted polypeptides are a fundamental biochemical axis of intercellular and endocrine communication. However, a global understanding of composition and dynamics of cellular secretomes in intact mammalian organisms has been lacking. Here, we introduce a proximity biotinylation strategy that enables...

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Detalles Bibliográficos
Autores principales: Wei, Wei, Riley, Nicholas M., Yang, Andrew C., Kim, Joon T., Terrell, Stephanie M., Li, Veronica L., Garcia-Contreras, Marta, Bertozzi, Carolyn R., Long, Jonathan Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904581/
https://www.ncbi.nlm.nih.gov/pubmed/33199915
http://dx.doi.org/10.1038/s41589-020-00698-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904581/
https://www.ncbi.nlm.nih.gov/pubmed/33199915
http://dx.doi.org/10.1038/s41589-020-00698-y

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