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Cell type-selective secretome profiling in vivo
Secreted polypeptides are a fundamental biochemical axis of intercellular and endocrine communication. However, a global understanding of composition and dynamics of cellular secretomes in intact mammalian organisms has been lacking. Here, we introduce a proximity biotinylation strategy that enables...
Autores principales: | Wei, Wei, Riley, Nicholas M., Yang, Andrew C., Kim, Joon T., Terrell, Stephanie M., Li, Veronica L., Garcia-Contreras, Marta, Bertozzi, Carolyn R., Long, Jonathan Z. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904581/ https://www.ncbi.nlm.nih.gov/pubmed/33199915 http://dx.doi.org/10.1038/s41589-020-00698-y |
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